Preventive screening of DNA in umbilical cord blood
Options in addition to stem cell deposit
The preventive screening includes additional DNA tests of the umbilical cord blood, which may be important to the health of your child when it grows older.
Screening for:
- Lactose intolerance
- Gluten intolerance
- Antibiotic intolerance
- AAT deficiency
- Hereditary fructose intolerance
Preventive screening of DNA by means of saliva sample
Irrespective of stem cell deposit
DNA diagnostics helps you to find out about predispositions to selected risks and intolerances at an early stage. Symptoms often develop only later in connection with external influences.
Screenings included from age 1.5 to 4 years:
- Lactose intolerance
- Gluten intolerance
- Antibiotic intolerance
- Hereditary fructose intolerance
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Even small children may suffer from intolerances, e.g. to gluten or lactose. If not diagnosed, this may cause troubles. The preventive screening checks whether your child belongs to the high-risk group. If this is the case, the pediatrician in attendance may advise special dietary tips and recommend preventive measures.
Gluten intolerance
Gluten is a protein composite found in the seed of cereal. The symptoms of this protein sensitivity, called celiac disease, often are digestion troubles. 95 percent of the affected persons show a specific genetic constellation, which is quickly discovered by means of the screening.
Lactose intolerance
Milk sugar (lactose) found in milk products, is split in the small intestine by the enzyme lactase to be absorbed. In the first months of life, this enzyme is fully developed for the baby being able to digest mother’s milk. In some people, the development of lactase may reduce. Consequences are e.g. indigestion, abdominal pain, diarrhea, or vomiting.
Antibiotic intolerance
If people are accordingly genetically predisposed, even the one-time taking of certain antibiotics (aminoglycosides) may cause permanent hearing damage or even deafness. If you know the risk because of the screening test, the pediatrician may take an alternative antibiotic – and the danger is averted.
AAT deficiency
If the body’s own inhibitor AAT is not available in sufficient quantities, damage to lungs and liver may be the result, if not treated. One of 2,000 children is affected by this AAT deficiency. If recognized early in our preventive screening (up to the age of 18 months), it can be balanced by means of an AAT drug. Health damage can thus be prevented in combination with other preventive measures.
Hereditary fructose intolerance
Hereditary fructose intolerance (HFI) is a condition that affects about one out of twenty thousand children by impairing the body’s ability to digest the ingested fruit sugar due to a mutation of the aldolase B gene. This causes toxic substances to build up, which inhibit the carbohydrate metabolism. Failure to thrive as well as liver and kidney damage may be the consequence. If your child suffers from HFI, your doctor in attendance may recommend the appropriate diet and preventive measures.